Author

T. J. Grunkemeyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. M. Patel· 2 shared E. N. G. Marsh· 2 shared R. T. Kennedy· 2 shared S. Ghosh· 2 shared A. B. Dumbrepatil· 1 shared A. I. Nesvizhskii· 1 shared J. Windak· 1 shared K. Sajja· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

A. M. Patel

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2 papers

Recent·Most cited

Viperin inhibits cholesterol biosynthesis and interacts with enzymes in the cholesterol biosynthetic pathway

T. J. Grunkemeyer, S. Ghosh, A. M. Patel, K. Sajja, J. Windak, V. Basrur, Y. S. Kim, A. I. Nesvizhskii, R. T. Kennedy, E. N. G. Marsh

This study shows viperin reduces cholesterol levels by inhibiting key enzymes in the biosynthetic pathway, though the exact mechanism remains unclear.

bioRxiv · Feb 19, 2021 · PreprintBiochemistry

The Interaction of Viperin with Hepatitis C Virus Non-Structural Protein 5A Inhibits the Catalytic Activity of Viperin

S. Ghosh, A. M. Patel, T. J. Grunkemeyer, A. B. Dumbrepatil, K. Zagalia, R. T. Kennedy, E. N. G. Marsh

This study shows viperin interacts with NS5A and VAP-33, reducing NS5A levels and viperin activity, suggesting NS5A evolved to inhibit ddhCTP synthesis.

bioRxiv · Oct 30, 2019 · PreprintBiochemistry