Author

T. J. Opperman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. E. Jerse· 1 shared A. Mehrani· 1 shared A. P. Heuck· 1 shared C. M. Dunham· 1 shared D. Hosangadi· 1 shared E. D. Hoffer· 1 shared E. J. Geddes· 1 shared H. Guo· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. E. Jerse

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell-based assay to determine Type 3 Secretion System translocon assembly in Pseudomonas aeruginosa using split luciferase

H. Guo, E. J. Geddes, T. J. Opperman, A. P. Heuck

The paper describes a cell-based assay using split luciferase to detect T3SS translocon assembly in Pseudomonas aeruginosa, showing high signal/noise ratio and robustness for inhibitor screening.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Z. D. Aron, A. Mehrani, E. D. Hoffer, K. L. Connolly, M. C. Torhan, J. N. Alumasa, P. Srinivas, M. Cabrera, D. Hosangadi, J. S. Barbor, S. C. Cardinale, S. M. Kwasny, L. R. Morin, M. M. Butler, T. J. Opperman, , K. C. Keiler

The paper describes the development of ribosome rescue inhibitors that clear drug-resistant Neisseria gonorrhoeae in vivo through a novel mechanism involving ribosomal conformational changes.

bioRxiv · Jun 4, 2020 · PreprintMicrobiology