Author

T. K. van den Berg

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. de jong· 1 shared B. van Steensel· 1 shared E. M. Janssen· 1 shared K. Franke· 1 shared M. Balzarolo· 1 shared M. Wolkers· 1 shared S. Engels· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. de jong

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1 paper

Recent·Most cited

ImmunologybioRxivAug 21, 2019

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner

M. Balzarolo, S. Engels, A. de jong…·M. Wolkers

This study shows that m6A methylation on specific DNA sequences enhances immune recognition by macrophages and dendritic cells through STING-dependent pathways, with sequence-specific immunostimulatory or suppressive effects.

DOI 10.1098/rsob.210030

mousehuman

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