Author

S. Engels

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. C. Wolkers· 3 shared A. Guislain· 2 shared B. P. Nicolet· 2 shared B. Popovic· 2 shared A. de jong· 1 shared A. Morales· 1 shared A. P. Jurgens· 1 shared A. Pareek· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersImmunology

M. C. Wolkers

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Author profile →

5 papers

Recent·Most cited

Regulation of IFNgamma production by ZFP36L2 in T cells is context-dependent

N. D. Zandhuis, A. Guislain, A. Popalzij, S. Engels, B. Popovic, M. Turner, M. C. Wolkers

This study shows ZFP36L2 regulates IFNγ production in T cells differently depending on activation context and time, by destabilizing Ifng mRNA in an AU-rich element-dependent manner.

bioRxiv · Feb 9, 2024 · PreprintImmunology

Effects of sub-lethal single, simultaneous, and sequential abiotic stresses on phenotypic traits of Arabidopsis thaliana

A. Morales, H. J. de Boer, J. C. Douma, S. Elsen, S. Engels, T. Glimmerveen, N. Sajeev, M. Huber, M. Luimes, E. Luitjens, K. Raatjes, C. Hsieh, J. Teapal, T. Wildenbeest, Z. Jiang, , R. Sasidharan

This study examines how sub-lethal abiotic stresses affect 12 phenotypic traits in Arabidopsis thaliana, finding additive and interactive effects across different stress combinations and accessions.

bioRxiv · Dec 10, 2021Plant Biology

Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function

B. Popovic, B. P. Nicolet, A. Guislain, S. Engels, A. P. Jurgens, N. Paravinja, J. J. Freen-van Heeren, F. P. van Alphen, M. van den Biggelaar, F. Salerno, M. C. Wolkers

The paper identifies RNA binding proteins regulating cytokine production in T cells over time, showing how they influence effector function and anti-tumor responses.

bioRxiv · Nov 3, 2021Immunology

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner

M. Balzarolo, S. Engels, A. de jong, K. Franke, T. K. van den Berg, E. M. Janssen, B. van Steensel, M. Wolkers

This study shows that m6A methylation on specific DNA sequences enhances immune recognition by macrophages and dendritic cells through STING-dependent pathways, with sequence-specific immunostimulatory or suppressive effects.

bioRxiv · Aug 21, 2019Immunology

Circular RNA expression in human hematopoietic cells is widespread and cell-type specific

B. P. Nicolet, S. Engels, F. Aglialoro, E. van den Akker, M. M. von Lindern, M. C. Wolkers

The paper analyzes circRNA expression in human hematopoietic cells, finding cell-type specific patterns and increased expression during maturation.

bioRxiv · Apr 12, 2018Immunology