Author

B. van Steensel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:Hi-C· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. de jong· 1 shared A. S. Belmont· 1 shared A. Vertii· 1 shared C.-Z. Zhang· 1 shared D. M. Gilbert· 1 shared D. Pellman· 1 shared D. Peric-Hupkes· 1 shared E. Jacob· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperImmunology

A. de jong

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Author profile →

3 papers

Recent·Most cited

Nucleolus and centromere TSA-Seq reveals variable localization of heterochromatin in different cell types

P. Kumar, O. Gholamalamdari, Y. Zhang, L. Zhang, A. Vertii, T. van Schaik, D. Peric-Hupkes, T. Sasaki, D. M. Gilbert, B. van Steensel, J. Ma, P. D. Kaufman, A. S. Belmont

The paper uses TSA-seq to map genomic regions near nucleoli and pericentric heterochromatin in human cell lines, revealing variable heterochromatin localization and complex nuclear organization.

bioRxiv · Oct 29, 2023Cell Biology

Transgenerational transcriptional heterogeneity from cytoplasmic chromatin

S. Papathanasiou, N. A. Mynhier, S. Liu, E. Jacob, E. Stokasimov, B. van Steensel, C.-Z. Zhang, D. Pellman

This study shows that micronuclei can cause heritable transcriptional changes by disrupting chromatin states, even after chromosomes are reincorporated into normal nuclei.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner

M. Balzarolo, S. Engels, A. de jong, K. Franke, T. K. van den Berg, E. M. Janssen, B. van Steensel, M. Wolkers

This study shows that m6A methylation on specific DNA sequences enhances immune recognition by macrophages and dendritic cells through STING-dependent pathways, with sequence-specific immunostimulatory or suppressive effects.

bioRxiv · Aug 21, 2019Immunology