A. de Jong

PLA2G15 is a Lysosomal BMP Hydrolase and Its Targeting Ameliorates Lysosomal Disease

This study identifies PLA2G15 as a lysosomal BMP hydrolase and shows its targeting improves lysosomal disease symptoms in NPC1 models.

Candida khanbhai sp. nov., a new clinically relevant yeast within the Candida haemulonii species complex

The paper describes a new yeast species, Candida khanbhai, within the Candida haemulonii complex and corrects the invalid descriptions of several related species.

Enrichment of novel Verrucomicrobia, Bacteroidetes and Krumholzibacteria in an oxygen-limited, methane- and iron-fed bioreactor inoculated with Bothnian Sea sediments

This study identifies novel microbial taxa involved in methane and iron cycling in a bioreactor using Bothnian Sea sediments under low oxygen conditions.

Alternative phage-host interaction in Lactococcus lactis: the carrier state drives rapid evolution of phages

The paper shows that a bacteriophage in Lactococcus lactis can transition from a carrier state to an active lytic cycle upon infection by a second phage, leading to rapid genomic evolution and host range diversification.

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner

This study shows that m6A methylation on specific DNA sequences enhances immune recognition by macrophages and dendritic cells through STING-dependent pathways, with sequence-specific immunostimulatory or suppressive effects.

Are Railways detrimental to bird populations? A BDACI study on the Construction of the Bothnia Line Railway

This study finds that railway construction did not significantly reduce bird biodiversity or abundance in impacted sites, contradicting common assumptions about railways being harmful to bird populations.

Decrease in Microbial Diversity Along a Pollution Gradient in Citarum River Sediment

The paper examines microbial diversity and nitrogen cycling in Citarum River sediment along a pollution gradient, finding reduced diversity and shifts in microbial phyla with increased pollution.