Author

T. Kuhn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Microbiology· 2 Cell Biology· 1 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Assay:fluorescence / live-cell microscopy· 4 Research Focus:chromatin & epigenetic regulation· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

J. C. M. Gebhardt· 6 shared D. Gonzalez· 4 shared P. Junier· 4 shared J. Hettich· 3 shared S. Bindschedler· 3 shared X.-Y. L. Richter· 3 shared J. Cossmann· 2 shared L. Streit· 2 shared

Activity by Year

2019-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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6 shared papersBiophysics

J. C. M. Gebhardt

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Author profile →

10 papers

Recent·Most cited

Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis

J. Cossmann, P. I. Kos, V. Varamogianni-Mamatsi, D. Assenheimer, T. Bischof, T. Kuhn, T. Vomhof, A. Papantonis, L. Giorgetti, J. C. M. Gebhardt

The paper investigates cohesin and CTCF chromatin binding dynamics during zebrafish embryogenesis, showing increased binding efficiency and its role in chromatin architecture formation.

bioRxiv · Dec 8, 2023Biophysics

A single Microcoleus species causes benthic cyanotoxic blooms worldwide

P. Junier, G. Cailleau, M. Fatton, P. Udriet, I. Hashmi, D. Bregnard, A. Corona-Ramirez, E. di Francesco, T. Kuhn, N. Mangia, S. Zhioua, D. Hunkeler, S. Bindschedler, S. Sieber, D. Gonzalez

The paper identifies a single Microcoleus species, Microcoleus anatoxicus, as the cause of benthic cyanotoxic blooms in multiple regions worldwide.

bioRxiv · Oct 13, 2023 · PreprintMicrobiology

Nutrients and flow shape the cyclic dominance games between Escherichia coli strains

T. Kuhn, P. Junier, R. Bshary, C. Terrettaz, D. Gonzalez, X.-Y. L. Richter

This study combines experiments and modeling to show that nutrients and flow rates influence cyclic dominance among three Escherichia coli strains, with toxin retention predicting competition outcomes.

bioRxiv · Aug 15, 2022 · PreprintEvolutionary Biology

Design and construction of 3D-printed devices to investigate active and passive bacterial dispersal on hydrated surfaces

T. Kuhn, M. Buffi, S. Bindschedler, P. Chain, D. Gonzalez, C. Stanley, L. Wick, P. Junier, X.-Y. L. Richter

This study designs 3D-printed devices to investigate bacterial dispersal on hydrated surfaces, showing that non-motile cells require flow or motile cells for dispersal.

bioRxiv · May 16, 2022Microbiology

Single-molecule tracking of Nodal and Lefty in live zebrafish embryos supports hindered diffusion model

T. Kuhn, A. N. Landge, D. Moersdorf, J. Cossmann, J. Gerstenecker, P. Mueller, J. C. M. Gebhardt

The paper uses single-molecule tracking to support the hindered diffusion model in zebrafish embryos by analyzing Nodal and Lefty diffusion dynamics.

bioRxiv · Apr 5, 2022Biophysics

Stress induced TDP-43 mobility loss independent of stress granules

L. Streit, T. Kuhn, T. Vomhof, A. C. Ludolph, J. H. Weishaupt, J. C. M. Gebhardt, J. Michaelis, K. M. Danzer

The paper investigates TDP-43 mobility under stress and recovery, finding stress-induced mobility loss in cytoplasm and nucleus, independent of stress granules.

bioRxiv · Feb 28, 2022Biophysics

Spatial scales of competition and a growth-motility tradeoff interact to determine bacterial coexistence

T. Kuhn, M. Mamin, S. Bindschedler, R. Bshary, A. Estoppey, D. Gonzalez, F. Palmieri, P. Junier, X.-Y. L. Richter

This study shows that spatial competition scales and a growth-motility tradeoff influence bacterial coexistence, with regional competition and dispersal networks promoting coexistence.

bioRxiv · Jan 5, 2022 · PreprintEcology

Single molecule tracking and analysis framework including theory-predicted parameter settings

T. Kuhn, J. Hettich, J. C. M. Gebhardt

The paper introduces TrackIt, a framework for single molecule tracking and analysis that addresses tracking errors and provides optimized parameters for reliable quantification of molecular dynamics.

bioRxiv · Nov 25, 2020Biophysics

Myosin VI moves on nuclear actin filaments and supports long-range chromatin rearrangements

A. Grosse-Berkenbusch, J. Hettich, T. Kuhn, N. Fili, A. W. Cook, Y. Hari-Gupta, A. Palmer, L. Streit, P. J. I. Ellis, C. Toseland, J. C. M. Gebhardt

This study shows nuclear myosin VI moves along actin filaments and facilitates transcription-dependent chromatin rearrangements.

bioRxiv · Apr 3, 2020 · PreprintCell Biology

Inferring quantity and qualities of superimposed reaction rates in single molecule survival time distributions

M. Reisser, J. Hettich, T. Kuhn, J. C. M. Gebhardt

This paper introduces GRID, a method to infer dissociation rates and frequencies from single molecule survival time distributions, and applies it to study CDX2 dissociation from chromatin.

bioRxiv · Jun 21, 2019Biophysics