Author

A. W. Cook

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Grosse-Berkenbusch· 2 shared J. C. M. Gebhardt· 2 shared N. Fili· 2 shared Y. Hari-Gupta· 2 shared A. dos Santos· 1 shared A. Palmer· 1 shared C. P. Toseland· 1 shared C. Toseland· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

A. Grosse-Berkenbusch

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Author profile →

3 papers

Recent·Most cited

First passage time study of DNA strand displacement

D. W. B. Broadwater, A. W. Cook, H. D. Kim

This study uses smFRET to analyze the kinetics of DNA strand displacement, finding sequence-dependent variations in displacement times and a single-step displacement time range of 30-300 microseconds.

Biophysical Journal · Jun 1, 2021Peer-reviewedBiophysics

Nuclear myosin VI regulates the spatial organization of mammalian transcription initiation.

Y. Hari-Gupta, N. Fili, A. dos Santos, A. W. Cook, R. E. Gough, H. C. W. Reed, L. Wang, J. Arron, T. Venit, E. Waite, A. Grosse-Berkenbusch, J. C. M. Gebhardt, P. Percipalle, T. L. Chew, M. L. Martin-Fernandez, C. P. Toseland

This study identifies nuclear myosin VI as a molecular anchor for RNA Polymerase II clusters, showing its role in maintaining transcription factory organization and gene expression.

bioRxiv · Apr 21, 2020Cell Biology

Myosin VI moves on nuclear actin filaments and supports long-range chromatin rearrangements

A. Grosse-Berkenbusch, J. Hettich, T. Kuhn, N. Fili, A. W. Cook, Y. Hari-Gupta, A. Palmer, L. Streit, P. J. I. Ellis, C. Toseland, J. C. M. Gebhardt

This study shows nuclear myosin VI moves along actin filaments and facilitates transcription-dependent chromatin rearrangements.

bioRxiv · Apr 3, 2020 · PreprintCell Biology