Author

T. Lautwein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Research Focus:differential expression· 4 Assay:scRNA-seq· 4 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2

Frequent Co-Authors

D. Schafflick· 2 shared H. Wiendl· 2 shared A. Borkhardt· 1 shared A. Hanel· 1 shared A. Heiligenhaus· 1 shared A. Lang· 1 shared A. Schulte-Mecklenbeck· 1 shared C. Alter· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

D. Schafflick

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape

V. H. Jepsen, A. Hanel, D. Picard, J. Mehtonen, R. Hasselmann, J. Schliehe-Diecks, K. Scharov, J.-W. Tu, R. Bhave, E. Kameri, N. Qin, H. Wang, Z. Zhuang, R. Wagener, L. Blümel, , U. Fischer

This study identifies H1-0 as a mediator of ETV6::RUNX1-induced quiescence in BCP-ALL preleukemic cells and suggests HDACi treatment as a potential therapeutic approach.

bioRxiv · Jun 28, 2024Cancer Biology

Intra-ocular dendritic cells are increased in HLA-B27 associated acute anterior uveitis

M. Kasper, M. Heming, D. Schafflick, X. Li, T. Lautwein, M. Meyer zu Horste, D. Bauer, K. Walscheid, H. Wiendl, K. Loser, A. Heiligenhaus, G. Meyer zu Hörste

The paper characterizes intraocular leukocyte infiltration in HLA-B27-associated uveitis using scRNA-seq, flow cytometry, and proteomics, revealing a unique dendritic cell infiltration pattern.

bioRxiv · Feb 16, 2021Immunology

Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted heart

J. Hesse, C. Owenier, T. Lautwein, R. Zalfen, J. F. Weber, Z. Ding, C. Alter, A. Lang, M. Grandoch, N. Gerdes, J. W. Fischer, G. W. Klau, C. Dieterich, K. Köhrer, J. Schrader

The paper uses single-cell RNA sequencing to identify distinct epicardial stromal cell populations in infarcted mouse hearts and their potential cardiomyogenic properties.

bioRxiv · Jan 26, 2021Cell Biology

Phloem loading via the abaxial bundle sheath cells in maize leaves

M. Bezrutczyk, N. Zoellner, C. P. S. Kruse, T. Hartwig, T. Lautwein, K.-E. Koehrer, W. B. Frommer, J.-Y. Kim

The paper identifies abaxial bundle sheath cells in maize as a key site for phloem loading via SWEET and UmamiT transporters, revealing a unique mechanism distinct from Arabidopsis.

bioRxiv · Sep 6, 2020Plant Biology

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

D. Schafflick, C. Xu Antelope, M. Hartlehnert, M. Cole, T. Lautwein, A. Schulte-Mecklenbeck, J. Wolbert, M. O. Heming, S. G. Meuth, T. Kuhlmann, C. C. Gross, H. Wiendl, N. Yosef, G. Meyer zu Horste

This study compares single-cell transcriptomes of blood and cerebrospinal fluid leukocytes in multiple sclerosis, identifying compartment-specific changes in cell types and transcriptional diversity.

bioRxiv · Apr 23, 2019Immunology