J.-Y. Kim

A novel GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 13 is involved in the Phosphate starvation-induced lipid remodeling in rice

This paper identifies OsGDPD13 as a gene involved in phosphate starvation-induced lipid remodeling in rice, showing its role in root development and phospholipid degradation under Pi deficiency.

Redirecting DNA repair for efficient CRISPR-Cas-based gene targeting in tomato

This study improves CRISPR-Cas gene targeting efficiency in tomato by suppressing nonhomologous end-joining and enhancing homologous recombination.

Glyoxalase 1: emerging biomarker and therapeutic target in cervical cancer progression

This study identifies Glyoxalase-1 (GLO1) as significantly upregulated in cervical cancer tissues and shows its role in cancer metabolism, suggesting it as a potential biomarker and therapeutic target.

Characterization of yield and fruit quality parameters of Vietnamese elite tomato lines generated through phenotypic selection and conventional breeding methods

This study develops ten elite tomato lines through conventional breeding, showing improved agronomical traits and virus resistance for agricultural use.

Decoding spatial organization maps and context-specific landscapes of breast cancer and its microenvironment via high-resolution spatial transcriptomic analysis

This study uses high-resolution spatial transcriptomics to analyze breast cancer and its microenvironment, revealing spatially distinct immune cell gradients and transcriptional differences between tumors.

Generation of parthenocarpic tomato plants in multiple elite cultivars using the CRISPR/Cas9 system

This study uses CRISPR/Cas9 to generate parthenocarpic tomato plants in elite cultivars, demonstrating high efficiency in producing homozygous knockout lines and enabling seed recovery through artificial fertilization.

Containing Cancer with Personalized Minimum Effective Dose

This study defines an effective dose window for cancer treatment that maintains tumor volume below a threshold by sustaining competition between drug-sensitive and resistant cells, using a deterministic model and patient-specific data.

Factor VII activating protease (FSAP) inhibits the outcome of ischemic stroke in mouse models.

This study shows that FSAP-SPD improves stroke outcomes in mice by enhancing clot lysis and reducing infarct volumes, while the inactive MI-isoform has no effect.

IRI-CCE: A Platform for Evaluating CRISPR-based Base Editing Tools and Its Components

The paper introduces IRI-CCE, a platform for evaluating CRISPR-based base editing tools in E. coli, showing different BE variants have distinct editing patterns based on promoter types.

The impact of the spatial heterogeneity of resistant cells and fibroblasts on treatment response

The paper develops an agent-based model to study how spatial distribution of resistant cells and fibroblasts affects the success of adaptive therapy over continuous therapy in cancer treatment.

α1-COP delivers sphingolipid modifiers and controls plasmodesmal callose deposition in Arabidopsis

The paper identifies α1-COP as a negative regulator of callose accumulation by modulating sphingolipid enzyme translocation in Arabidopsis.

Association between toothbrushing and non-alcoholic fatty liver disease

This study finds that higher toothbrushing frequency is inversely associated with non-alcoholic fatty liver disease (NAFLD) in Korean adults, particularly in smokers and diabetics.

Unique and distinct identities and functions of leaf phloem cells revealed by single cell transcriptomics

This study uses single-cell transcriptomics to identify and characterize distinct vascular cell types in Arabidopsis leaves, revealing unique functions of phloem parenchyma cells.

Phloem loading via the abaxial bundle sheath cells in maize leaves

The paper identifies abaxial bundle sheath cells in maize as a key site for phloem loading via SWEET and UmamiT transporters, revealing a unique mechanism distinct from Arabidopsis.

Glucosylhydroxyceramides Modulate Secretion Machinery of a Subset of Plasmodesmata Proteins and a Change in the Callose Accumulation

This study shows that changes in glucosylhydroxyceramides affect callose accumulation by disrupting the secretory machinery of GPI-anchored PD proteins.

Altitudinal range-size distribution of breeding birds and environmental factors for the determination of species richness: An empirical test of altitudinal Rapoports rule and rescue effect on a local scale

This study tests altitudinal Rapoports rule and rescue effect by analyzing species range-size distribution and environmental factors, finding support for Rapoports rule and climatic hypothesis but not ambient energy hypothesis.