Author

T. Martinu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Approach:deep learning· 2 Assay:flow cytometry· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

S. Keshavjee· 4 shared J. Yeung· 3 shared M. Liu· 3 shared S. C. Juvet· 3 shared S. Moshkelgosha· 3 shared A. Duong· 2 shared B. Joe· 2 shared B. Renaud-Picard· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersImmunology

S. Keshavjee

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Author profile →

5 papers

Recent·Most cited

Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure

S. Moshkelgosha, L. Levy, S. Safavi, S. Karunagaran, G. Wilson, B. Renaud-Picard, G. Madu, R. Ramchandani, J. Oliver, T. Watanabe, K. F. Bei, B. Joe, Q. Li, E. Huszti, M. Cheung, , S. Juvet

The paper identifies CD4+CD57+PD1+ T cells in lung transplant recipients that predict allograft dysfunction and are associated with fibrosis in both human and mouse models.

bioRxiv · Dec 19, 2023Immunology

Interferon-stimulated and metallothionein-expressing macrophages are associated with acute and chronic allograft dysfunction after lung transplantation

S. Moshkelgosha, A. Duong, G. Wilson, T. Andrews, G. Berra, B. Renaud-Picard, M. Liu, S. Keshavjee, S. MacParland, J. Yeung, T. Martinu, S. C. Juvet

The paper identifies two macrophage subsets in lung transplant recipients associated with acute and chronic allograft dysfunction using single-cell RNA sequencing.

bioRxiv · Jun 14, 2021Immunology

Pro-inflammatory alveolar macrophages associated with allograft dysfunction after lung transplantation

S. Moshkelgosha, , G. W. Wilson, A. Duong, T. S. Andrews, B. Renaud, G. Berra, M. Liu, S. Keshavjee, T. Martinu, S. MacParland, J. Yeung, S. C. Juvet

The paper uses scRNA-seq to analyze BAL cells from lung transplant patients, identifying pro-inflammatory macrophage subsets linked to allograft dysfunction.

bioRxiv · Mar 3, 2021 · PreprintImmunology

Ex vivo delivery of regulatory T cells for control of alloimmune priming in the donor lung

E. Miyamoto, A. Takahagi, A. Ohsumi, T. Martinu, D. Hwang, K. Boonstra, B. Joe, M. Juan Umana, K. Bei, D. Vosoughi, M. Liu, M. Cypel, S. Keshavjee, S. C. Juvet

This study shows that ex vivo delivery of regulatory T cells to donor lungs before transplantation can suppress alloimmune responses and improve lung graft outcomes in a rat model.

bioRxiv · Feb 7, 2021Immunology

A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome

A. K. Shum, Z. Deng, Z. Chong, C. S. Law, K. Mukai, F. O. Ho, T. Martinu, B. J. Backes, W. L. Eckalbar, T. Taguchi

This study shows that defective COPI transport of STING due to COPA mutations leads to immune dysregulation and type I interferon signaling in COPA syndrome.

bioRxiv · May 20, 2020Immunology