Defining ancestry, heritability and plasticity of cellular phenotypes in somatic evolution
J. S. Schiffman, A. R. D'Avino, T. Prieto, Y. Pang, Y. Fan, S. Rajagopalan, C. Potenski, T. Hara, M. L. Suva, C. Gawad, D. A. Landau
The paper introduces PATH, a framework to quantify heritability and plasticity of cellular phenotypes in somatic evolution using single-cell data from mouse and human samples.
bioRxiv · Dec 28, 2022Evolutionary Biology