Author

T. R. Docking

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Karsan· 2 shared A. Kumar· 1 shared A. S. Tam· 1 shared A. Shanks· 1 shared A. Y.-C. Mo· 1 shared D. G. Bernard· 1 shared D. Wood· 1 shared E. Willie· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. Karsan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loss of FBXO11 function establishes a stem cell program in acute myeloid leukemia through dysregulation of the mitochondrial LONP1

A. Y.-C. Mo, H. Kincross, X. Wang, L. Y.-T. Chang, G. Duns, F. Mey, Z. Zhu, H. Kwan, T. Lau, T. R. Docking, J. Tran, S. Colborne, S.-W. G. Cheng, S. Huang, N. Gharaee, , A. Karsan

This study identifies FBXO11 loss as a driver of AML by promoting a stem cell program through mitochondrial dysregulation.

bioRxiv · Sep 10, 2022 · PreprintCancer Biology

DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

A. S. Tam, S. Tsai, E. Y.-C. Chang, V. Mathew, A. Shanks, T. R. Docking, A. Kumar, D. G. Bernard, A. Karsan, P. C. Stirling

This study shows SF3B1 mutations cause DYNLL1 mis-splicing, leading to genome instability through altered DNA repair and PARP inhibitor sensitivity.

bioRxiv · May 26, 2021 · PreprintCell Biology