Author

T. Rosales

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2

Frequent Co-Authors

F. Cai· 2 shared P. Kapur· 2 shared R. J. DeBerardinis· 2 shared A. B. Aurora· 1 shared A. Bagrodia· 1 shared A. D. Rao· 1 shared A. Kaushik· 1 shared A. Leach· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

F. Cai

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2 papers

Recent·Most cited

Mitochondrial metabolism in primary and metastatic human kidney cancers

D. Bezwada, R. J. DeBerardinis, N. P. Lesner, B. Brooks, H. S. Vu, Z. Wu, L. Cai, S. Kasitinon, S. Kelekar, F. Cai, A. B. Aurora, M. Patrick, A. Leach, R. Ghandour, Y. Zhang, , V. Margulis

This study investigates mitochondrial metabolism in kidney cancers, finding that primary tumors have suppressed mitochondrial function while metastases show enhanced TCA cycle labeling.

bioRxiv · Feb 6, 2023Cancer Biology

In-vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma

A. Kaushik, L. K. Burroughs, A. Tarangelo, M. Ragavan, C.-Y. Wu, X. Li, K. Ahumada, V. T. Tcheuyap, F. Saatchi, Q. Do, C. Yong, T. Rosales, C. Stevens, A. D. Rao, B. Faubert, , R. J. DeBerardinis

The paper identifies multiple glutamine metabolism pathways in ccRCC tumorgrafts and shows that targeting amidotransferase activity reduces tumor growth.

bioRxiv · Oct 31, 2022Cancer Biology