Author

N. P. Lesner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Mishra· 2 shared R. J. DeBerardinis· 2 shared S. House· 2 shared A. B. Aurora· 1 shared A. Bagrodia· 1 shared A. Frank· 1 shared A. Leach· 1 shared A. M. Poole· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

P. Mishra

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Author profile →

2 papers

Recent·Most cited

Mitochondrial metabolism in primary and metastatic human kidney cancers

D. Bezwada, R. J. DeBerardinis, N. P. Lesner, B. Brooks, H. S. Vu, Z. Wu, L. Cai, S. Kasitinon, S. Kelekar, F. Cai, A. B. Aurora, M. Patrick, A. Leach, R. Ghandour, Y. Zhang, , V. Margulis

This study investigates mitochondrial metabolism in kidney cancers, finding that primary tumors have suppressed mitochondrial function while metastases show enhanced TCA cycle labeling.

bioRxiv · Feb 6, 2023Cancer Biology

Differential requirements for mitochondrial electron transport chain components in the adult murine liver

N. P. Lesner, X. Wang, Z. Chen, A. Frank, C. Menezes, S. House, S. D. Shelton, D. G. McFadden, J. Wansapura, R. J. DeBerardinis, P. Mishra

This study investigates the tissue-specific roles of mitochondrial complex I and IV in adult mouse liver, finding that complex I loss is tolerated while complex IV dysfunction causes metabolic and functional impairments.

bioRxiv · Jul 15, 2021Cell Biology