Author

T. S. Carroll

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Annibali· 1 shared A. F. Stenzel· 1 shared A. Gola· 1 shared A. Hodgkinson· 1 shared A. J. Hudspeth· 1 shared A. Nagiel· 1 shared A. Peace· 1 shared A. Pinharanda· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

A. Annibali

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

J. Le Pen, G. Paniccia, V. Kinast, M. Moncada-Velez, A. W. Ashbrook, M. Bauer, H.- H. Hoffmann, A. Pinharanda, I. Ricardo-Lax, A. F. Stenzel, E. A. Rosado-Olivieri, K. H. Dinnon, W. C. Doyle, C. A. Freije, S.-H. Hong, , C. M. Rice

The paper identifies PLSCR1 as a host factor restricting SARS-CoV-2 entry, which recent variants have evolved to bypass, through a CRISPR screen and integration of genetic studies.

bioRxiv · Feb 16, 2024Immunology

Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs

N. R. Kastan, S. Oak, R. Liang, L. Baxt, R. W. Myers, J. Ginn, N. Liverton, D. J. Huggins, J. Pichardo, M. Paul, T. S. Carroll, A. Nagiel, K. Gnedeva, A. J. Hudspeth

This paper describes the development of a more potent Lats kinase inhibitor, TDI-011536, which promotes cell proliferation and regeneration in mammalian tissues.

bioRxiv · Apr 7, 2022Cell Biology

The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

E. Fuchs, B. Hurwitz, N. Guzzi, A. Gola, V. F. Fiore, A. Sendoel, M. Nikolova, D. Barrows, T. S. Carroll, H. A. Pasolli

This study shows that the integrated stress response (ISR) redirects translation to centrosomal proteins to clear unfolded proteins at the microtubule organizing center during proteotoxic stress in SCC stem cells.

bioRxiv · Feb 13, 2022Cell Biology

Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function

B. C. Wilson, L. Boehme, A. Annibali, A. Hodgkinson, T. S. Carroll, R. J. Oakey, V. C. Seitan

This study identifies Zbtb11 as a mitochondrial regulator that interacts with NRF-2/GABP to maintain mitochondrial function and shows its disruption leads to intellectual disability.

bioRxiv · Dec 13, 2019Cell Biology