Author

T. S. Kyaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. Sandy· 2 shared A. A. Yayanos· 1 shared A. N. Goga· 1 shared A. Venook· 1 shared B. A. Methe· 1 shared B. G. H. Guthrie· 1 shared C. Atreya· 1 shared D. Gempis· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

M. Sandy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors

T. S. Kyaw, M. Sandy, K. Trepka, J. Goh, K. Yu, V. Dimassa, E. Bess, J. Bisanz, P. J. Turnbaugh

The gut bacterium Eggerthella lenta secretes inhibitors of P-glycoprotein ATPase activity, accelerating drug absorption.

bioRxiv · Oct 13, 2022Microbiology

A conserved enzyme found in diverse human gut bacteria interferes with anticancer drug efficacy

P. Spanogiannopoulos, T. S. Kyaw, B. G. H. Guthrie, P. H. Bradley, J. V. Lee, J. Melamed, Y. N. A. Malig, K. N. Lam, D. Gempis, M. Sandy, W. Kidder, E. L. van Blarigan, C. Atreya, A. Venook, R. R. Gerona, , P. Turnbaugh

The paper shows that a conserved enzyme in gut bacteria inactivates anticancer drugs, reducing their efficacy in mice and highlighting microbial contributions to drug metabolism.

bioRxiv · May 2, 2022 · PreprintMicrobiology

Distinctive Gene and Protein Characteristics of Extremely Piezophilic Colwellia

L. M. Peoples, T. S. Kyaw, J. U. Ugalde, K. K. Mullane, R. A. Chastain, A. A. Yayanos, M. Kusube, B. A. Methe, D. H. Bartlett

This study identifies genomic and proteomic adaptations in piezophilic Colwellia strains that enable survival in high-pressure deep-sea environments.

bioRxiv · Mar 15, 2020Microbiology