Author

T. Seufferlein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Kleger· 2 shared A. Lehel· 1 shared B. Sainz· 1 shared C. Conzelmann· 1 shared C. Guenes· 1 shared D. Schuetz· 1 shared E. Rodriguez-Aznar· 1 shared E. Tabares· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

A. Kleger

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells

K. Walter, E. Rodriguez-Aznar, M. S. Ventura-Ferreira, P. O. Frappant, T. Dittrich, K. Tiwary, S. Meessen, L. Lerma, N. Daiss, L. A. Schulte, F. Arnold, N. Azoitei, M. Erkan, A. Lehel, T. Bruemmendorf, , P. C. Hermann

This study shows that telomerase activity and stemness factors form a feedback loop that maintains pancreatic cancer stem cells, and disrupting this loop reduces their tumorigenic potential.

bioRxiv · Nov 2, 2020 · PreprintCancer Biology

Remdesivir but not famotidine inhibits SARS-CoV-2 replication in human pluripotent stem cell-derived intestinal organoids

J. Krueger, R. Gross, C. Conzelmann, J. A. Mueller, L. Koepke, K. Sparrer, D. Schuetz, T. Seufferlein, T. F. E. Barth, S. Stenger, S. Heller, A. Kleger, J. Muench

This study uses human intestinal organoids to show that remdesivir inhibits SARS-CoV-2 replication, while famotidine does not.

bioRxiv · Jun 10, 2020 · PreprintMicrobiology