On-rate modulation of cadherin interactions by chemical fragments
A. Senoo, S. Ito, S. Nagatoishi, Y. Saito, G. Ueno, K. Yoshida, T. Tashima, S. Kudo, S. Sando, K. Tsumoto
This study identifies a chemical fragment that modulates the on-rate of P-cadherin dimerization by inhibiting cell adhesion.
bioRxiv · Aug 30, 2020Biochemistry