Author

A. Senoo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1

Frequent Co-Authors

K. Tsumoto· 4 shared J. M. M. Caaveiro· 3 shared S. Nagatoishi· 3 shared S. Ito· 2 shared S. Kudo· 2 shared S. Yanaka· 2 shared A. Ishii-Watabe· 1 shared A. M. Blackwell· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersBiochemistry

K. Tsumoto

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis

A. M. Blackwell, Y. Jami-Alahmadi, A. S. Nasamu, S. Kudo, A. Senoo, C. Slam, K. Tsumoto, J. A. Wohlschlegel, J. M. M. Caaveiro, D. E. Goldberg, P. A. Sigala

This study identifies PfHO as essential for apicoplast biogenesis and gene expression in Plasmodium falciparum, revealing its role in maintaining apicoplast-encoded RNA levels.

bioRxiv · May 30, 2024Biochemistry

Characterization of high affinity IgM and IgG monoclonal antibodies against norovirus variants GII.4 and GII.17

J. Tagawa, S. Yanaka, Y. Kato, A. Masuda, J. M. Lee, A. Senoo, K. Oyama, M. Nishida, T. Kusakabe, J. M. M. Caaveiro

This study generates and characterizes monoclonal IgM and IgG antibodies against norovirus variants GII.4 and GII.17, revealing differences in binding mechanisms and affinity.

bioRxiv · May 11, 2024Biochemistry

Key role of P230 in the hinge region on the IgG architecture and function

Y. Koseki, Y. Yamaguchi, M. Aoyama, M. Tada, A. Senoo, A. Ishii-Watabe, T. Uchihashi, S. Uchiyama, K. Kato, S. Yanaka, J. M. M. Caaveiro

This study investigates the role of Pro230 in the hinge region of IgG by deleting it, revealing structural changes and functional effects on FcγRI-mediated activity.

bioRxiv · May 10, 2024 · PreprintBiophysics

Lipid nanodiscs facilitate the identification of a fragment compound inhibiting the enzymatic activity of the bacterial membrane protein MsbA.

K. Fujimoto, A. Senoo, S. Nagatoishi, T. Ueda, K. Tsumoto, J. Caaveiro

This study uses lipid nanodiscs and surface plasmon resonance to identify a fragment compound that inhibits MsbA's ATPase activity, suggesting a pathway for developing stronger inhibitors.

bioRxiv · Jun 15, 2021 · PreprintBiophysics

Structural basis for binding mechanism of human serum albumin complexed with cyclic peptide dalbavancin

S. Ito, A. Senoo, S. Nagatoishi, M. Ohue, M. Yamamoto, K. Tsumoto, N. Wakui

This study determines the crystal structure of human serum albumin bound to dalbavancin, revealing the binding mechanism and structural changes involved.

bioRxiv · Sep 9, 2020Biochemistry

On-rate modulation of cadherin interactions by chemical fragments

A. Senoo, S. Ito, S. Nagatoishi, Y. Saito, G. Ueno, K. Yoshida, T. Tashima, S. Kudo, S. Sando, K. Tsumoto

This study identifies a chemical fragment that modulates the on-rate of P-cadherin dimerization by inhibiting cell adhesion.

bioRxiv · Aug 30, 2020Biochemistry