Author

T. U. Marron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

M. Merad· 4 shared S. Gnjatic· 4 shared A. Tabachnikova· 3 shared A. Wolf· 3 shared E. Kenigsberg· 3 shared R. Flores· 3 shared S. Kim-Schulze· 3 shared A. H. Rahman· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersCancer Biology

M. Merad

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single cell view of tumor microenvironment gradients in pleural mesothelioma

B. Giotti, K. Dolasia, w. Zhao, P. Cai, R. Sweeney, E. Merritt, E. Kiner, G. Kim, A. Bhagwat, S. Hegde, B. Fitzgerald, S. Shroff, T. Dawson, M. Garcia-Barros, J. Abdul-Ghafar, , A. Tsankov

This paper uses single-cell RNA-sequencing to analyze the tumor microenvironment in pleural mesothelioma, identifying gene programs, fetal-like endothelial cells, and a new therapeutic target.

bioRxiv · Mar 14, 2024Cancer Biology

Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade

A. Magen, P. Hamon, N. Fiaschi, L. Troncoso, E. Humblin, D. D'souza, T. Dawson, M. D. Park, J. Kim, S. Hamel, M. Buckup, C. Chang, A. Tabachnikova, H. Schwartz, N. Malissen, , Merad

The paper identifies intratumoral niches involving mregDC and CXCL13+ Th cells that support CD8 T cell differentiation following PD-1 blockade in HCC patients.

bioRxiv · Jun 22, 2022 · PreprintImmunology

Spatial positioning and matrix programs of cancer-associated fibroblasts promote T cell exclusion in human lung tumors

J. A. Grout, P. Sirven, A. M. Leader, S. Maskey, E. Hector, I. Puisieux, F. Steffan, E. Cheng, N. Tung, M. Maurin, R. Vaineau, L. Karpf, M. Plaud, M. Casanova-Acebes, A. Tabachnikova, , H. Salmon

The paper identifies two CAF subsets in human lung tumors that promote T cell exclusion through distinct matrix programs and spatial organization.

bioRxiv · Jan 20, 2022Cancer Biology

Structurally and functionally distinct early antibody responses predict COVID-19 disease trajectory and mRNA vaccine response

S. Chakraborty, J. C. Gonzalez, B. L. Sievers, V. Mallajosyula, M. Dubey, Y.-L. B. Cheng, K. Q. T. Tran, S. Chakraborty, A. Cassidy, S. T. Chen, A. Sinnott, T. Gelbart, Y. Golan, M. Prahl, U. Singh, , T. T. Wang

The paper identifies early antibody responses that predict COVID-19 severity and vaccine response, showing functional differences in inflammation regulation.

bioRxiv · May 25, 2021 · PreprintImmunology

CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations

A. M. Leader, J. A. Grout, C. Chang, B. Maier, A. Tabachnikova, L. Walker, A. Lansky, J. LeBerichel, N. Malissen, M. Davila, J. Martin, G. Magri, K. Tuballes, Z. Zhoa, F. Petralia, , M. Merad

The paper analyzes CITEseq data from NSCLC lesions to identify an immune cell activation module linked to tumor antigen load and TP53 mutations.

bioRxiv · Jul 16, 2020 · PreprintImmunology