Author

T. Van Nieuwenhuysen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:Xenopus· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. Creytens· 2 shared D. Tulkens· 2 shared K. Vleminckx· 2 shared S. Demuynck· 2 shared B. Alman· 1 shared C. Vanhove· 1 shared D. Dimitrakopoulou· 1 shared J. Przybyl· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

D. Creytens

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2 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 17, 2021

CRISPR-SID: identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping

T. Naert, D. Tulkens, T. Van Nieuwenhuysen…·K. Vleminckx

This paper introduces CRISPR-SID, a method to identify tumor dependencies in Xenopus models, revealing EZH2 as a druggable target for desmoid tumors.

DOI 10.1073/pnas.2115116118

XenopusCRISPR screen

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 15, 2021

Engraftment of allotransplantated tumour cells in adult rag2 mutant Xenopus tropicalis

D. Tulkens, D. Dimitrakopoulou, T. Van Nieuwenhuysen…·K. Vleminckx

This paper establishes a Xenopus tropicalis model for studying human cancer by generating a rag2-/- knock-out line and optimizing irradiation protocols for tumor cell engraftment.

DOI 10.1101/2021.11.15.468684

Xenopusgenetic perturbation / CRISPR

𝕏 PostBluesky