Author

T. von Heyl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:chicken / avian· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Schusser· 3 shared H. Sid· 2 shared R. Klinger· 2 shared A. Kheimar· 1 shared A. Schlickenrieder· 1 shared B. B. Kaufer· 1 shared B. Boehm· 1 shared B. Schade· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

B. Schusser

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3 papers

Recent·Most cited

Unraveling the role of γδ T cells in the pathogenesis of an oncogenic avian herpesvirus

M. A. Sabsabi, A. Kheimar, Y. You, D. von La Roche, S. Härtle, T. W. Göbel, T. von Heyl, B. Schusser, B. B. Kaufer

This study shows that γδ T cells restrict Marek's disease virus replication and tumor formation in chickens by reducing viral load in key lymphoid organs.

bioRxiv · Dec 5, 2023Microbiology

Genetic Reinstatement of RIG-I in Chickens Reveals Insights into Avian Immune Evolution and Influenza Interaction

H. Sid, T. von Heyl, S. Schleibinger, R. Klinger, L. Heyemelot Nabel, H. K. Vikkula, R. Guabiraba, V. Guillory, R. Scicluna, M. M. Alhussien, B. Boehm, B. Schade, D. Elleder, S. Sives, L. Vervelde, , B. Schusser

This study reinstates RIG-I and RNF135 in chickens to investigate their role in avian influenza response, finding that their expression exacerbates inflammation and mortality without affecting viral replication.

bioRxiv · Nov 1, 2023Immunology

Knockout of αβ but not γδ T cells in chickens is associated with high cytotoxicity and deficiency of regulatory and helper T cells

T. von Heyl, R. Klinger, D. Aumann, C. Zenner, M. Alhussien, A. Schlickenrieder, K. Lengyel, H.-K. Vikkula, T. Mittermair, H. Sid, B. Schusser

This study generates chicken T cell knockout models to investigate their roles, finding that β T cell loss causes severe immunological defects while γδ T cell loss does not.

bioRxiv · Mar 10, 2023Immunology