Author

R. Guabiraba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:chicken / avian· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

B. J. Ferguson· 3 shared C. E. Bryant· 2 shared D. R. Rodrigues· 2 shared M. Oliveira· 2 shared S. Trapp· 2 shared V. Guillory· 2 shared A. Bafica· 1 shared B. Boehm· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

B. J. Ferguson

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4 papers

Recent·Most cited

Genetic Reinstatement of RIG-I in Chickens Reveals Insights into Avian Immune Evolution and Influenza Interaction

H. Sid, T. von Heyl, S. Schleibinger, R. Klinger, L. Heyemelot Nabel, H. K. Vikkula, R. Guabiraba, V. Guillory, R. Scicluna, M. M. Alhussien, B. Boehm, B. Schade, D. Elleder, S. Sives, L. Vervelde, , B. Schusser

This study reinstates RIG-I and RNF135 in chickens to investigate their role in avian influenza response, finding that their expression exacerbates inflammation and mortality without affecting viral replication.

bioRxiv · Nov 1, 2023Immunology

Mechanisms of type I interferon production by chicken TLR21

R. Guabiraba, D. R. Rodrigues, P. T. Manna, M. Chollot, V. Saint-Martin, S. Trapp, M. Oliveira, C. E. Bryant, B. J. Ferguson

This study investigates how chicken TLR21 triggers type I interferon production in macrophages, revealing conserved signaling pathways with mammalian TLR9.

bioRxiv · Sep 20, 2023Immunology

Chicken cGAS senses fowlpox virus infection and regulates macrophage effector function

M. Oliveira, D. R. Rodrigues, V. Guillory, E. Kut, E. S. Giotis, M. A. Skinner, R. Guabiraba, C. E. Bryant, B. J. Ferguson

This study shows that chicken cGAS detects fowlpox virus DNA, triggering type-I interferon production and regulating macrophage effector functions like MHC-II expression.

bioRxiv · Oct 1, 2020Immunology

ISG15 induces IL-10 production in human monocytes and is a biomarker of disease severity during active tuberculosis

P. F. dos Santos, J. Van Weyenbergh, M. Delgobo, D. d. O. Patricio, B. J. Ferguson, R. GUABIRABA, T. Dierckx, S. M. M. MENEZES, A. Bafica, D. S. Mansur

The paper shows ISG15 induces IL-10 in human monocytes and correlates with TB disease severity.

bioRxiv · Aug 2, 2017Immunology