Author

S. Sives

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:chicken / avian· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Assay:CUT&Tag· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

L. Vervelde· 3 shared B. Boehm· 1 shared B. H. Thompson· 1 shared B. Schade· 1 shared B. Schusser· 1 shared C. Sharp· 1 shared D. Borowska· 1 shared D. Elleder· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

L. Vervelde

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic Reinstatement of RIG-I in Chickens Reveals Insights into Avian Immune Evolution and Influenza Interaction

H. Sid, T. von Heyl, S. Schleibinger, R. Klinger, L. Heyemelot Nabel, H. K. Vikkula, R. Guabiraba, V. Guillory, R. Scicluna, M. M. Alhussien, B. Boehm, B. Schade, D. Elleder, S. Sives, L. Vervelde, , B. Schusser

This study reinstates RIG-I and RNF135 in chickens to investigate their role in avian influenza response, finding that their expression exacerbates inflammation and mortality without affecting viral replication.

bioRxiv · Nov 1, 2023Immunology

Disentangling the Innate Immune Responses of Intestinal Epithelial Cells and Lamina Propria Cells to Salmonella Typhimurium Infection in Chickens

K. Sutton, T. Nash, S. Sives, D. Borowska, J. Mitchell, P. Vohra, M. Stevens, L. Vervelde

This study compares innate immune responses in 2D and 3D chicken enteroids infected with Salmonella Typhimurium, showing that 3D models better mimic in vivo responses due to the presence of lamina propria cells.

bioRxiv · Jul 14, 2023 · PreprintImmunology

CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy

C. Sharp, B. H. Thompson, T. J. Nash, O. Lee, R. M. Pinto, L. Thorley, Y.-T. Lin, S. Sives, H. Wise, S. M. R. Clohisey, F. Grey, L. Vervelde, P. Simmonds, P. Digard, E. R. Gaunt

This paper engineers an influenza A virus with increased CpG content, showing it is attenuated in mice but replication competent in vaccine propagation systems, suggesting a new strategy for live attenuated vaccines.

bioRxiv · Apr 29, 2022Microbiology