Author

T. Worzfeld

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Assay:flow cytometry· 1

Frequent Co-Authors

S. Offermanns· 2 shared A. Javed· 1 shared A. Kumanogoh· 1 shared A. Oleksy· 1 shared A. Pradeep· 1 shared A. R. Clarke· 1 shared A. Scialdone· 1 shared B. Gottgens· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

S. Offermanns

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence

D. Toghani, S. Zeng, E. Mahammadov, E. I. Crosse, N. Seyedhassantehrani, C. Burns, D. Gravano, S. Radtke, H.-P. Kiem, S. Rodriguez, N. Carlesso, A. Pradeep, N. K. Wilson, S. J. Kinston, B. Gottgens, , L. Silberstein

This study identifies Sema4A as a critical niche factor required for myeloid-biased HSC self-renewal and long-term persistence under stress.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

Plexin-B1 mutation drives prostate cancer metastasis

B. Shorning, N. Trent, D. F. Griffiths, T. Worzfeld, S. Offermanns, J. Masters, A. R. Clarke, M. J. Smalley, M. Williamson

This study shows that a Plexin-B1 mutation promotes prostate cancer metastasis and identifies it as a potential therapeutic target.

bioRxiv · Jul 19, 2020 · PreprintCancer Biology

Mechanochemical control of epidermal stem cell divisions by B-plexins

C. Jiang, A. Javed, L. Kaiser, M. M. Nava, D. Zhao, D. T. Brandt, J. Fernandez-Baldovinos, L. Zhou, C. Hoess, K. Sawmynaden, A. Oleksy, D. Matthews, L. S. Weinstein, H.-J. Groene, C. M. Niessen, , T. Worzfeld

This study identifies B-plexins as critical for mechanosensing in epidermal stem cells, linking mechanical feedback to cell division control during development and in cancer.

bioRxiv · Apr 30, 2020Cell Biology