Author

T. Wyss-Coray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Brunet· 1 shared A. McGeever· 1 shared A. McKay· 1 shared A. O. Pisco· 1 shared B. Lehallier· 1 shared C. Franceschi· 1 shared C. L. Dekker· 1 shared C. N. Bedbrook· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Brunet

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease

C.-C. Chou, R. Vest, M. A. Prado, J. Wilson-Grady, J. A. Paulo, Y. Shibuya, P. Moran-Losada, T.-T. Lee, J. Luo, S. P. Gygi, J. W. Kelly, D. Finley, M. Wernig, T. Wyss-Coray, J. Frydman

This study uses transdifferentiated neurons to show lysosomal deficits are an early event in aging and Alzheimer's disease, leading to proteotoxic deposits and cell death.

bioRxiv · Mar 27, 2023Cell Biology

An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning

A. McKay, E. K. Costa, J. Chen, C.-K. Hu, X. Chen, C. N. Bedbrook, R. C. Khondker, M. Thielvoldt, P. P. Singh, T. Wyss-Coray, A. Brunet

The paper introduces an automated feeding system for African killifish to study dietary restriction effects on lifespan and cognitive behavior, showing sex-specific transcriptome changes and extending male lifespan.

eLife · Nov 10, 2022Peer-reviewedPhysiology

A Single Cell Transcriptomic Atlas Characterizes Aging Tissues in the Mouse

The Tabula Muris Consortium, A. O. Pisco, A. McGeever, N. Schaum, J. Karkanias, N. F. Neff, S. Darmanis, T. Wyss-Coray, S. R. Quake

This study creates a single cell transcriptomic atlas of aging mouse tissues, identifying age-related changes in cell types and organ composition across 23 tissues.

bioRxiv · Feb 21, 2020 · PreprintCell Biology

An Inflammatory Clock Predicts Multi-morbidity, Immunosenescence and Cardiovascular Aging in Humans

N. Sayed, T. Gao, R. j. Tibshirani, T. Hastie, L. Cui, T. Kuznetsova, Y. Rosenberg-Hasson, R. Ostan, D. Monti, B. Lehallier, S. Shen-Orr, H. Maecker, C. L. Dekker, T. Wyss-Coray, C. Franceschi, , D. Furman

The paper develops an inflammatory clock of aging (iAge) using blood immunome data from 1001 individuals, showing it correlates with multi-morbidity, immunosenescence, and cardiovascular aging.

bioRxiv · Nov 16, 2019 · PreprintImmunology