Author

M. Wernig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Y. Shibuya· 2 shared A. Bruckner· 1 shared A. Brunet· 1 shared A. Christiano· 1 shared A. Cramer· 1 shared A. E. Oro· 1 shared A. L. S. Chang· 1 shared A. Moore· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Y. Shibuya

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease

C.-C. Chou, R. Vest, M. A. Prado, J. Wilson-Grady, J. A. Paulo, Y. Shibuya, P. Moran-Losada, T.-T. Lee, J. Luo, S. P. Gygi, J. W. Kelly, D. Finley, M. Wernig, T. Wyss-Coray, J. Frydman

This study uses transdifferentiated neurons to show lysosomal deficits are an early event in aging and Alzheimer's disease, leading to proteotoxic deposits and cell death.

bioRxiv · Mar 27, 2023Cell Biology

A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa

G. Neumayer, J. Torkelson, S. Li, K. McCarthy, H. Zhen, M. Vangipuram, J. Jackow, A. Rami, C. Hansen, Z. Guo, S. Gaddam, A. Pappalardo, L. Li, A. Cramer, K. Roy, , A. E. Oro

This paper develops a scalable, GMP-compatible cell therapy for Dystrophic Epidermolysis Bullosa using CRISPR-corrected iPS cells to generate functional skin grafts.

bioRxiv · Feb 28, 2023 · PreprintBioengineering

The Autism Risk Factor CHD8 Is a Chromatin Activator and Functionally Dependent on the ERK-MAPK Pathway Effector ELK1

B. Haddad Derafshi, T. Danko, S. Chanda, P. Batista, U. Litzenburger, Q. Y. Lee, Y. H. Ng, A. Sebin, H. Y. Chang, T. C. Sudhof, M. Wernig

This study identifies CHD8 as a chromatin activator in human neurons that depends on the ERK-MAPK pathway effector ELK1 for its function.

bioRxiv · Nov 10, 2020Cell Biology

Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals

S. Mahmoudi, E. Mancini, A. Moore, L. Xu, F. Jahanbani, K. Hebestreit, R. Srinivasan, X. Li, K. Devarajan, L. Prelot, C. E. Ang, Y. Shibuya, B. A. Benayoun, A. L. S. Chang, M. Wernig, , A. Brunet

This study shows that old fibroblasts secrete inflammatory cytokines, leading to variability in reprogramming efficiency and affecting wound healing in older individuals.

bioRxiv · Oct 19, 2018 · PreprintCell Biology