Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
S. Lim, N. Boyer, N. Boo…·A. W. Partridge
This paper identifies macrocyclic peptides that inhibit KRAS signaling by binding to its hydrophobic pocket, showing on-target activity and improved proteolytic stability.
S. Kannan, P. G. A. Aronica, S. Ng…·A. Partridge
This paper combines macrocyclization and D-amino acid strategies to create an all-D helical peptide with improved target affinity and cellular activity.
S. Ng, Y.-C. Juang, A. Chandramohan…·D. P. Lane
This paper identifies false-positive peptide inhibitors of KRas using orthogonal assays and cellular screens, highlighting the need for rigorous validation in drug discovery.