T.-Y. Feng

Demonstration of chemotherapeutic mediated lymphatic changes in meningeal lymphatics in vitro, ex vivo, and in vivo

This study demonstrates that systemic chemotherapy can disrupt meningeal lymphatics, with differential effects observed between platinum and taxane chemotherapies.

Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia

The paper identifies metabolic dysregulation in T. gondii infection-induced cachexia, showing increased sphingolipids and phosphatidylcholines and decreased TCA cycle intermediates in mouse sera.

Reciprocal interactions between the gut microbiome and mammary tissue mast cells promote metastatic dissemination of HR+ breast tumors

This study shows that an inflammatory gut microbiome promotes early metastasis of HR+ breast tumors by increasing mast cell activity in mammary tissue.