Author

Tachianna Griffiths

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:virus· 2 Research Focus:database / resource· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea N. LoesiD· 3 shared Caroline KikawaiD· 3 shared Elizabeth M. DrapeauiD· 3 shared Jesse D. BloomiD· 3 shared John HuddlestoniD· 3 shared Scott E. HensleyiD· 3 shared Trevor BedfordiD· 3 shared Benjamin John CowlingiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Andrea N. LoesORCID

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Author profile →

3 papers

Recent·Most cited

Strain-specific differences in the response to egg-derived versus recombinant protein influenza vaccines

Andrea N. Loes, Rosario Araceli L Tarabi, Shuk Hang Li, Reilly K. Atkinson, John Huddleston, Caroline Kikawa, Tachianna Griffiths, Elizabeth M. Drapeau, Sook‐San Wong, SW Cheng, Nancy Leung, Sarah E. Cobey, Benjamin John Cowling, Trevor Bedford, Scott E. Hensley, Jesse D. Bloom

This study compares neutralizing antibody titers from egg-derived and recombinant protein influenza vaccines against diverse H1N1 strains, finding that egg-derived vaccines induce less boost against a new clade with specific antigenic mutations.

Journal of Virology · May 27, 2026Peer-reviewedImmunology

High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains

Caroline Kikawa, Andrea N. Loes, John Huddleston, Marlin D Figgins, Philippa L. Steinberg, Tachianna Griffiths, Elizabeth M. Drapeau, Heidi Peck, Ian Barr, Janet A. Englund, Scott E. Hensley, Trevor Bedford, Jesse D. Bloom

A sequencing-based neutralization assay across 78 H3N2 HA strains and 150 sera shows strain growth in 2023 tracks the fraction of sera with low titers, but not pooled-serum titers.

eLife · Feb 23, 2026Peer-reviewedEvolutionary Biology✦ In-depth digest

Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection

Caroline Kikawa, John Huddleston, Samuel A. Turner, Andrea N. Loes, Jiaojiao Liu, Sydney Gang, Tachianna Griffiths, Elizabeth M. Drapeau, Benjamin John Cowling, Faith C. S. Ho, Nancy Leung, Janet A. Englund, Kirsten Lacombe, Shinji Watanabe, Hideki Hasegawa, , Jesse D. Bloom

Sequencing-based neutralization of 91 H3N2 and H1N1 hemagglutinins against 302 human sera (27,409 titers) shows reduced titers to H3N2 subclade K and H1N1 D.3.1.1.

Virus Evolution · Jan 1, 2026Peer-reviewedMicrobiology✦ In-depth digest