Author

Taichi Umeyama

Kyushu University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Hideyuki NakashimaiD· 2 shared Kinichi NakashimaiD· 2 shared Mikio HoshinoiD· 2 shared Satoshi MiyashitaiD· 2 shared Alex Savchenko· 1 shared Aline de Lima LeiteiD· 1 shared Aline Maria Araújo MartinsiD· 1 shared Alysson Renato MuotriiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Hideyuki NakashimaORCID

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2 papers

Recent·Most cited

STING restrains calcium-dependent microglial phagocytosis and protects against neuronal loss and cognitive impairment during epileptogenesis

Yuka Kasahara, Hideyuki Nakashima, Satoshi Miyashita, Taichi Umeyama, Yasuhiro Nakano, Soichiro Kumamoto, Kazuhiko Kawata, Keisuke Imabayashi, Yoshihiro Baba, Koji Kobiyama, Ken J. Ishii, Takahiro Sato, Yoshikazu Johmura, Mikio Hoshino, Kinichi Nakashima

This study shows that STING inhibits microglial phagocytosis and protects neurons during epileptogenesis by regulating calcium signaling through the STING-STIM1-SOCE axis.

bioRxiv · Jun 30, 2026 · PreprintNeuroscience

Dormant viral pathways underlie space-induced neural senescence: a neuroprotective strategy for spaceflight and neurological diseases

Aline Maria Araújo Martins, Hideyuki Nakashima, Ángela Macia, Taichi Umeyama, Satoshi Miyashita, Livia LS Nascimento, Luisa Bulcao Vieira Coelho, Pinar Mesci, Erik Viirre, Nicole Suarez, Aurian Saleh, Alex Savchenko, Beatriz Freitas, Aline de Lima Leite, Diego M. Assis, , Alysson Renato Muotri

The paper shows that spaceflight triggers neural senescence via reactivation of dormant viral-like retroelements, and that reverse transcriptase inhibitors can reverse these effects.

bioRxiv · Nov 2, 2025 · PreprintNeuroscience