Pinar Mesci

This study shows that SETD5 dysfunction in astrocytes increases IL-6, which harms neurons via JAK/STAT signaling, suggesting therapeutic targeting of this pathway for ASD and ID.

The paper shows that spaceflight triggers neural senescence via reactivation of dormant viral-like retroelements, and that reverse transcriptase inhibitors can reverse these effects.

The paper demonstrates the fabrication of DNA-inspired Janus base nanomaterials in space, showing their potential for in-space manufacturing.

SARS-CoV-2 infects and kills neural cells in iPSC-derived human brain organoids and impairs synaptogenesis; the approved antiviral sofosbuvir is reported to reverse both effects.

This study shows that exosomes from control neural cultures can rescue neural development defects in Rett Syndrome by influencing neuron number, apoptosis, and synaptic function.