Author
Institute of Medical Science, The University of TokyoORCID 0000-0002-3492-117XUnclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Yuka Kasahara, Hideyuki Nakashima, Satoshi Miyashita…·Kinichi Nakashima
This study shows that STING inhibits microglial phagocytosis and protects neurons during epileptogenesis by regulating calcium signaling through the STING-STIM1-SOCE axis.
Hisato Kobayashi, Tatsushi Igaki, Soichiro Kumamoto…·Kazuki Kurimoto
The paper shows that an ancestral LTR retrotransposon insertion in the common ancestor of Euarchontoglires drives lineage-specific genomic imprinting of ZDBF2 through post-fertilization transcription initiation.
Julien Richard Albert, Toshihiro Kobayashi, Azusa Inoue…·Hisato Kobayashi
The paper identifies imprinted genes in rat tissues, finds conservation of canonical imprints in embryos but divergence in extra-embryonic tissues, and discovers novel non-canonical imprints.
Ryota Miyashita, Atsuya Nishiyama, Weihua Qin…·Makoto Nakanishi
This study identifies USP7 and ATAD5 as key factors in terminating UHRF1-dependent PAF15 ubiquitin signaling, linking this process to the completion of maintenance DNA methylation.
Soichiro Kumamoto, Atsuya Nishiyama, Yoshie Chiba…·Makoto Nakanishi
The paper shows that PARP1-HPF1-dependent ADP-ribosylation recruits LIG3-XRCC1 to chromatin to mediate Okazaki fragment joining when LIG1 is absent.