Author

Takehiro Otoshi

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Akihiro MiuraiD· 1 shared Anri Sawada· 1 shared Ayyappa Kumar Sista KameshwariD· 1 shared Benjamin D. Kotton· 1 shared Chyuan‐Sheng LiniD· 1 shared Dai ShimizuiD· 1 shared Finn J HawkinsiD· 1 shared Hemanta SarmahiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Akihiro MiuraORCID

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2 papers

Recent·Most cited

Genetic background and transient prenatal disruption of vitamin A signaling determine susceptibility to airway hyperresponsiveness in mice

Takehiro Otoshi, Ayyappa Kumar Sista Kameshwar, Benjamin D. Kotton, Yoshinori Seki, Zachary Cardell, Xiangyi Ke, Yuta Matsuno, Pooja Rajaram, Youn‐Kyung Kim, Sarah M. Sharpton, Loredana Quadro, Wellington Veras Cardoso, Masako Suzuki

The paper shows that genetic background and prenatal vitamin A disruption influence airway hyperresponsiveness in mice through TGFβ-activating mesenchymal cells.

bioRxiv · Oct 31, 2025 · PreprintDevelopmental Biology

Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes generation of the whole lung

Akihiro Miura, Hemanta Sarmah, Junichi Tanaka, Youngmin Hwang, Anri Sawada, Yuko Shimamura, Takehiro Otoshi, Yuri Kondo, Yinshan Fang, Dai Shimizu, Zurab Ninish, Jake A. Le Suer, Nicole C. Dubois, Jennifer Davis, Shinichi Toyooka, , Munemasa Mori

The paper identifies the Foxa2 lineage's role in lung development and demonstrates that conditional complementation of this lineage can generate a whole lung in mice.

eLife · Oct 20, 2023Peer-reviewedDevelopmental Biology