Author

Takumi Nagakura

International Research Center for Medical Sciences, Kumamoto University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Eiichiro YamamotoiD· 2 shared Kei MorikawaiD· 2 shared Kenichi TsujitaiD· 2 shared Shinsuke HanataniiD· 2 shared Yasuhiro IzumiyaiD· 2 shared Yuichiro ArimaiD· 2 shared Akira Fujiyama· 1 shared Fumihiko OgataiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersPhysiology

Eiichiro YamamotoORCID

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Author profile →

2 papers

Recent·Most cited

IL-17A Mediates Cardiac Hypertrophy in Chronic Kidney Disease through the IL-23/Th17 Axis.

Fumihiko Ogata, Shinsuke Hanatani, Yuki Okuno, Masahiro Yamamoto, Kei Morikawa, Takumi Nagakura, Satoshi Araki, Eiichiro Yamamoto, Yuichiro Arima, Yasuhiro Izumiya, Kenichi Tsujita

This study shows that IL-17A promotes cardiac hypertrophy in CKD via the IL-23/Th17 axis, with IL-12p40 as a potential biomarker and therapeutic target.

bioRxiv · Sep 23, 2026 · PreprintPhysiology

Hepatic Ketogenesis Attenuates Cardiac Hypertrophy via Metabolic Reprogramming

Toshihiro Yamada, Kei Morikawa, Akira Fujiyama, Takumi Nagakura, Yuqing Xu, Miho Kataoka, Terumasa Umemoto, Miki Bundo, Kazuya Iwamoto, Zeeshan Ahmed, Suvi Linna-Kuosmanen, Shinsuke Hanatani, Hiroki Usuku, Yasushi Matsuzawa, Yasuhiro Izumiya, , Yuichiro Arima

This study shows that hepatic ketogenesis reduces cardiac hypertrophy in HFpEF by maintaining beta-hydroxybutyrate levels, which modulate myocardial metabolism.

bioRxiv · Feb 2, 2026 · PreprintBiochemistry