Author

Thorkell Andressen

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anver Basha ShaikiD· 1 shared Jordan L. MeieriD· 1 shared Joycelyn H. Williams· 1 shared K. HuberiD· 1 shared Kiall F. SuazoiD· 1 shared Ludwig G. BaueriD· 1 shared Manini S. Penikalapati· 1 shared McKenna C. CrawfordiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Anver Basha ShaikORCID

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1 paper

Recent·Most cited

Paralogue-selective degradation of the lysine acetyltransferase EP300

Xuemin Chen, McKenna C. Crawford, Ying Xiong, Anver Basha Shaik, Kiall F. Suazo, Ludwig G. Bauer, Manini S. Penikalapati, Joycelyn H. Williams, K. Huber, Thorkell Andressen, Rolf E. Swenson, Jordan L. Meier

This study develops a small molecule, MC-1, that selectively degrades EP300 over CREBBP, revealing factors governing paralogue-specific degradation and its impact on cancer cell proliferation.

JACS Au · Jul 29, 2024Peer-reviewedBiochemistry