Author

McKenna C. Crawford

National Cancer InstituteORCID 0000-0002-3274-1255Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Jordan L. MeieriD· 2 shared Acong YangiD· 1 shared Anatoly Kustanovich· 1 shared Anver Basha ShaikiD· 1 shared Beverly A. MockiD· 1 shared Bogdan V. PolevodaiD· 1 shared Chelsea Sanders· 1 shared Christine N. MilleriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Jordan L. MeierORCID

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2 papers

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedMar 19, 2025

Transfer RNA acetylation regulates in vivo mammalian stress signaling

Supuni Thalalla Gamage, Roxane Khoogar, Shereen A. Howpay Manage…·Jordan L. Meier

This study shows that tRNA acetylation regulates stress signaling in mammals by affecting ribosome function and interacting with the Gcn2 kinase.

18 citationstop 3%

mouseexperimental assay

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BiochemistryJACS AuPeer-reviewedJul 29, 2024

Paralogue-selective degradation of the lysine acetyltransferase EP300

Xuemin Chen, McKenna C. Crawford, Ying Xiong…·Jordan L. Meier

This study develops a small molecule, MC-1, that selectively degrades EP300 over CREBBP, revealing factors governing paralogue-specific degradation and its impact on cancer cell proliferation.

12 citations

humanproteomics

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