Author

Tim C. Elston

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

Aarav MehtaiD· 1 shared Alison M. Rojas· 1 shared Caroline A Tomblin· 1 shared Christina Ford· 1 shared Dalia FleifeliD· 1 shared Elizabeth BrunkiD· 1 shared Jeanette Gowen CookiD· 1 shared Jeremy E. PurvisiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Aarav MehtaORCID

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1 paper

Recent·Most cited

Extrachromosomal DNA Gives Cancer a New Evolutionary Pathway

Yue Wang, Oliver Cope, Jingting Chen, Aarav Mehta, Dalia Fleifel, Christina Ford, Poorya Behnamie, Molly Murray, Santiago Haase, Saygin Gulec, Logan Slade, Tim C. Elston, Philip M. Spanheimer, Caroline A Tomblin, Alison M. Rojas, , Elizabeth Brunk

The paper shows that ecDNA allows tumors to adapt rapidly by maintaining a spectrum of gene expression levels across cells, rather than relying on clonal expansion.

bioRxiv · Apr 26, 2025 · PreprintGenomics