Author

Toshiko Tanaka

National Institute on Aging

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Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Giovanna FantoniiD· 2 shared Julián CandiaiD· 2 shared Luigi FerrucciiD· 2 shared Aarno Palotie· 1 shared Abhishek K. Sarkar· 1 shared Albert V. Smith· 1 shared Albertine J. Oldehinkel· 1 shared Alexander Teumer· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Giovanna FantoniORCID

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Author profile →

3 papers

Recent·Most cited

The blood proteome predicts the impact of circulating factors on age-related mitochondrial health

Stephanie Heimler, Jaclyn Bergstrom, Nina Sun, Toshiko Tanaka, Ann Zenobia Moore, Julián Candia, Brian H. Chen, Qu Tian, Arsun Bektas, Giovanna Fantoni, Christopher Dunn, Mary Kaileh, Ranjan Sen, Luigi Ferrucci, Anthony J. A. Molina

The paper develops a proteomic signature, MitoAge, that predicts age-related mitochondrial health based on circulating factors in serum.

npj Aging · Jul 24, 2026Peer-reviewedCell Biology

Effects of in vitro hemolysis and repeated freeze-thaw cycles in protein abundance quantification using the SomaScan and Olink assays

Julián Candia, Giovanna Fantoni, Ruin Moaddel, Francheska Delgado‐Peraza, Nader Shehadeh, Toshiko Tanaka, Luigi Ferrucci

This study evaluates how in vitro hemolysis and freeze-thaw cycles affect protein abundance measurements in SomaScan and Olink assays, identifying affected analytes and proposing quality control measures.

Journal of Proteome Research · Apr 18, 2025Peer-reviewedMolecular Biology

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

Felix R. Day, Deborah J. Thompson, Hannes Helgason, Daniel I. Chasman, Hilary Finucane, Patrick Sulem, Katherine S. Ruth, Sean Whalen, Abhishek K. Sarkar, Eva Albrecht, Elisabeth Altmaier, Marzyeh Amini, Caterina M. Barbieri, Thibaud Boutin, Archie Campbell, , John R.B Perry

This study identifies 389 genetic signals for age at menarche and finds BMI-independent causal links between puberty timing and cancer risks.

bioRxiv · Sep 23, 2016 · PreprintGenomics