Brian H. Chen

The paper develops a proteomic signature, MitoAge, that predicts age-related mitochondrial health based on circulating factors in serum.

mLiftOver converts DNA methylation data between Infinium platforms, enabling accurate integration and analysis across different array versions.

This study uses transfer learning to predict blood DNA methylation biomarkers from saliva data, improving accuracy over traditional methods for 20 out of 26 biomarkers.

This paper develops a high-throughput DNA methylation array and atlas for mice, revealing tissue-specific methylation patterns and their associations with aging, differentiation, and disease.

This study identifies 242 genetic loci for glycaemic traits using trans-ancestry meta-analysis, finding 99 novel loci and improved fine-mapping resolution compared to single-ancestry analyses.

This study identifies genetic variants associated with epigenetic age acceleration and shows TERT's role in regulating the DNA methylation clock.