Author

U. Duvvuri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

A. Yassin-Kassab· 2 shared N. Wang· 2 shared R. A. Harbison· 2 shared A. Gopalkrishnan· 1 shared A. VYAS· 1 shared C. Kurukulasuriya· 1 shared D. Faden· 1 shared D. Palmer· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. Yassin-Kassab

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3 papers

Recent·Most cited

Polyamine transport inhibition and cisplatin synergistically enhance tumor control through oxidative stress in murine head and neck cancer models

A. Yassin-Kassab, N. Wang, J. R. Foley, T. R. Murray Stewart, M. R. Burns, R. A. Casero, R. A. Harbison, U. Duvvuri

This study shows that combining cisplatin with AMXT-1501 enhances tumor control in HNSCC models by increasing oxidative stress and apoptosis, independent of polyamine levels.

bioRxiv · Jul 25, 2023Cancer Biology

Lysosomal mitochondrial interaction promotes tumor growth in squamous cell carcinoma of the head and neck

A. Gopalkrishnan, N. Wang, S. Cruz-Rangel, A. Yassin-Kassab, S. Shiva, C. Kurukulasuriya, S. P. Monga, R. J. DeBerardinis, K. Kiselyov, U. Duvvuri

This study shows that lysosomal-mitochondrial interaction (LMI) promotes tumor growth in squamous cell carcinoma of the head and neck by enhancing mitochondrial complex I activity and lysosomal function.

bioRxiv · Jun 25, 2023Cancer Biology

Recurrent human papillomavirus-related head and neck cancer undergoes metabolic re-programming and is driven by oxidative phosphorylation

A. VYAS, R. A. Harbison, D. Faden, M. Kubik, D. Palmer, Q. Zhang, H. Osmanbeyoglu, E. Mendez, U. Duvvuri

This study identifies oxidative phosphorylation as a driver of treatment failure in recurrent HPV-related head and neck cancer, highlighting Nrf2 as a therapeutic target.

bioRxiv · Aug 21, 2020Cancer Biology