Author

U. Warpman Berglund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Hagenkort· 1 shared A. Pettke· 1 shared A. Stolz· 1 shared A.-S. Jemth· 1 shared C. E. Strom· 1 shared C. Gokturk· 1 shared C. Kalderen· 1 shared E. Homan· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Hagenkort

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2 papers

Recent·Most cited

A phenomics approach for in vitro antiviral drug discovery

J. Rietdijk, M. Tampere, A. Pettke, P. Georgiev, M. Lapins, U. Warpman Berglund, O. Spjuth, M.-R. Puumalainen, J. Carreras-Puigvert

This paper introduces a phenomics approach combining Cell Painting and antibody-based detection to screen antiviral drugs in infected cells, showing effective compounds reverse morphological changes.

bioRxiv · Jan 13, 2021Pharmacology & Toxicology

MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells

H. Gad, O. Mortusewicz, S. G. Rudd, A. Stolz, N. Amaral, L. Brautigam, L. Pudelko, K. Sanjiv, C. Kalderen, A.-S. Jemth, I. Almlof, T. Visnes, N. Schultz, J. Bostrom, J. M. Calderon Montano, , T. Helleday

This study identifies MTH1's role in mitosis and shows that potent MTH1 inhibitors cause mitotic arrest by disrupting tubulin polymerization and suppressing ROS.

bioRxiv · Sep 5, 2019 · PreprintCancer Biology