Dynamic Kinetochore Size Regulation Promotes Microtubule Capture And Chromosome Biorientation In Mitosis
C. Sacristan, M. Ahmad, J. Keller, J. Fermie, V. Groenewold, E. Tromer, A. Fish, R. Melero, J. M. Carazo, J. Klumperman, A. Musacchio, A. Perrakis, G. J. Kops
The paper shows that Spindly-based dynamic regulation of kinetochore size ensures proper microtubule capture and chromosome segregation by controlling corona expansion and shedding.
bioRxiv · Mar 12, 2018Cell Biology