Author

J. M. Carazo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Approach:deep learning· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. O. S. Sorzano· 3 shared D. Maluenda· 2 shared E. Ramirez-Aportela· 2 shared J. Vargas· 2 shared P. Conesa· 2 shared R. Marabini· 2 shared R. Melero· 2 shared A. Cuervo· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBiophysics

C. O. S. Sorzano

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin

C. Cacho-Navas, C. Lopez-Pujante, N. Reglero-Real, N. Colas-Algora, A. Cuervo, J. J. Conesa, S. Barroso, S. Ciordia, A. Paradela, G. D'Agostino, C. Manzo, J. Feito, G. Andres, F. Molina-Jimenez, P. Majano, , J. Millan

This study shows ICAM-1 nanoclusters control hepatic epithelial cell polarity through actomyosin regulation, independent of leukocyte adhesion.

bioRxiv · Jul 18, 2023Cell Biology

FSC-Q: A CryoEM map-to-atomic model quality validation based on the local Fourier Shell Correlation

E. Ramirez-Aportela, D. Maluenda, Y. C. Fonseca, P. Conesa, R. Marabini, J. B. Heymann, J. M. Carazo, C. O. S. Sorzano

This paper introduces FSC-Q, a method to assess local map-to-model fit in cryoEM by comparing local FSC values from full and half maps, helping to avoid overfitting.

bioRxiv · May 12, 2020Biophysics

Automatic local resolution-based sharpening of cryo-EM maps.

E. Ramirez-Aportela, J. L. Vilas, R. Melero, P. Conesa, M. Martinez, D. Maluenda, J. Mota, A. Jimenez, J. Vargas, R. Marabini, J. M. Carazo, C. O. S. Sorzano

This paper introduces a new automatic method for sharpening cryo-EM maps based on local resolution, improving map quality and interpretability.

bioRxiv · Oct 2, 2018Biophysics

ENRICH: a fast method to improve the quality of flexible macromolecular reconstructions

M. Kazemi, C. O. S. Sorzano, A. Des Georges, J. M. Carazo, J. Vargas

ENRICH improves 3D map quality from small, heterogeneous cryo-EM datasets by merging particles across conformations using optical flow.

bioRxiv · Aug 26, 2018Bioengineering

Dynamic Kinetochore Size Regulation Promotes Microtubule Capture And Chromosome Biorientation In Mitosis

C. Sacristan, M. Ahmad, J. Keller, J. Fermie, V. Groenewold, E. Tromer, A. Fish, R. Melero, J. M. Carazo, J. Klumperman, A. Musacchio, A. Perrakis, G. J. Kops

The paper shows that Spindly-based dynamic regulation of kinetochore size ensures proper microtubule capture and chromosome segregation by controlling corona expansion and shedding.

bioRxiv · Mar 12, 2018Cell Biology