EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake
C. Matthaeus, I. Lahmann, S. Kunz, W. Jonas, A. A. Melo, M. Lehmann, E. Larsson, R. Lundmark, M. Kern, M. Blueher, V. Hauke, D. N. Mueller, A. Schuermann, C. Birchmeier, O. Daumke
This study shows that EHD2 restricts caveolar dynamics to regulate lipid uptake, with loss of EHD2 leading to increased fat accumulation and obesity in mice.
bioRxiv · Mar 7, 2019Cell Biology