Author

A. A. Melo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

O. Daumke· 2 shared A. Frost· 1 shared A. Schuermann· 1 shared C. Birchmeier· 1 shared C. M.T. Spahn· 1 shared C. Matthaeus· 1 shared C. van Hoorn· 1 shared D. N. Mueller· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

O. Daumke

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Author profile →

3 papers

Recent·Most cited

Cryo-electron tomography reveals structural insights into the membrane binding and remodeling activity of dynamin-like EHDs

A. A. Melo, T. Sprink, J. Noel, E. Vazquez Sarandeses, C. van Hoorn, J. Loerke, C. M.T. Spahn, O. Daumke

The paper uses cryo-electron tomography to determine the structure of EHD4 filaments on a membrane, revealing insights into their remodeling activity.

bioRxiv · Sep 20, 2021 · PreprintBiophysics

Photocatalytic plant LPOR forms helical lattices that shape membranes for chlorophyll synthesis

H. C. Nguyen, A. A. Melo, J. Kruk, A. Frost, M. Gabruk

This study reveals the atomic structure of LPOR assemblies and shows how they shape membranes and catalyze chlorophyll synthesis in plants.

bioRxiv · Aug 19, 2020Biophysics

EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake

C. Matthaeus, I. Lahmann, S. Kunz, W. Jonas, A. A. Melo, M. Lehmann, E. Larsson, R. Lundmark, M. Kern, M. Blueher, V. Hauke, D. N. Mueller, A. Schuermann, C. Birchmeier, O. Daumke

This study shows that EHD2 restricts caveolar dynamics to regulate lipid uptake, with loss of EHD2 leading to increased fat accumulation and obesity in mice.

bioRxiv · Mar 7, 2019Cell Biology