Author

C. Birchmeier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

I. Lahmann· 2 shared A. A. Melo· 1 shared A. Schuermann· 1 shared A. Steffen· 1 shared C. Matthaeus· 1 shared D. N. Mueller· 1 shared E. D. Lowenstein· 1 shared E. Larsson· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

I. Lahmann

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Author profile →

4 papers

Recent·Most cited

The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling

L. Pelz, L. Dossou, N. Kompier, R. Juttner, G. Siemonsmeier, N. Meyer, E. D. Lowenstein, I. Lahmann, H. Kettenmann, C. Birchmeier, F. G. Rathjen

This study shows that BT-IgSF is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling, with knockout leading to increased connexin43 clustering and reduced coupling.

bioRxiv · Jun 17, 2022 · PreprintCell Biology

SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta

M. Kirchenwitz, S. Stahnke, S. Prettin, M. Borowiak, C. Birchmeier, K. Rottner, T. E. B. Stradal, A. Steffen

The paper identifies SMER28 as a compound that inhibits PI3K p110 delta and disrupts receptor tyrosine kinase signaling, leading to autophagy induction and reduced cell growth.

bioRxiv · Dec 10, 2021Cell Biology

Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation

M. Kim, Y. Zhang, C. Birchmeier

The paper shows that fructose 1,6-bisphosphate sensed by PKM2 regulates MyoD stability and myogenic differentiation by modulating Huwe1 localization.

bioRxiv · Dec 22, 2020 · PreprintCell Biology

EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake

C. Matthaeus, I. Lahmann, S. Kunz, W. Jonas, A. A. Melo, M. Lehmann, E. Larsson, R. Lundmark, M. Kern, M. Blueher, V. Hauke, D. N. Mueller, A. Schuermann, C. Birchmeier, O. Daumke

This study shows that EHD2 restricts caveolar dynamics to regulate lipid uptake, with loss of EHD2 leading to increased fat accumulation and obesity in mice.

bioRxiv · Mar 7, 2019Cell Biology