Cancer BiologybioRxiv
Radiotherapy and cisplatin increase immunotherapy efficacy by enabling local and systemic intratumoral T-cell activity
P. Kroon, E. Frijlink, V. Iglesias-Guimarais…·I. Verbrugge
This study shows radiotherapy and cisplatin enhance immunotherapy efficacy in breast cancer by overcoming PD-1-independent T-cell suppression in the tumor microenvironment.
DOI 10.1158/2326-6066.cir-18-0654