Author

P. Kroon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

B. Oldrini· 2 shared M. Squatrito· 2 shared A. Izzo· 1 shared A. Volkov· 1 shared C. Marques· 1 shared D.-H. Nam· 1 shared E. F. Wagner· 1 shared E. Frijlink· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

B. Oldrini

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3 papers

Recent·Most cited

NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

C. Marques, T. Unterkircher, P. Kroon, A. Izzo, Y. Dramaretska, E. Kling, B. Oldrini, O. Schnell, S. Nelander, E. F. Wagner, L. Bakiri, G. Gargiulo, M. S. Carro, M. Squatrito

The paper identifies FOSL1 as a key regulator of mesenchymal glioblastoma subtype through NF1 modulation, showing its role in plasticity and aggressiveness.

bioRxiv · Nov 6, 2020Cancer Biology

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

B. Oldrini, N. Vaquero-Siguero, Q. Mu, P. Kroon, Y. Zhang, M. Galan-Ganga, Z. Bao, Z. Wang, H. Liu, J. K. Sa, J. Zhao, H. Kim, S. Rodriguez-Perales, D.-H. Nam, R. G. Verhaak, , M. Squatrito

This study shows that MGMT genomic rearrangements cause TMZ resistance in gliomas and can be detected in exosomes as potential recurrence markers.

Nature Communications · Aug 4, 2020Peer-reviewedCancer Biology

Radiotherapy and cisplatin increase immunotherapy efficacy by enabling local and systemic intratumoral T-cell activity

P. Kroon, E. Frijlink, V. Iglesias-Guimarais, A. Volkov, M. van Buuren, T. N. Schumacher, M. Verheij, J. Borst, I. Verbrugge

This study shows radiotherapy and cisplatin enhance immunotherapy efficacy in breast cancer by overcoming PD-1-independent T-cell suppression in the tumor microenvironment.

bioRxiv · Jun 29, 2018Cancer Biology